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| The movie on the right shows CO2 reaching and passing through its critical point (31°C / 74bar). Notice as the CO2 becomes supercritical the meniscus disappears, indicating there is no longer a distinction between liquid and gas. The meniscus returns as it is taken back below the critical point. |
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| The second movie shows what effect supercritical CO2 has on PLGA (a polymer approved by the regulatory agencies for drug delivery). As you will see, as the CO2 becomes supercritical, the polymer liquefies. |
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| The next movie shows a short burst of atomisation of a polymer/drug mixture. By careful nozzle selection and control of the atomisation environment, we can control particle formation.
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Reproduced with kind permission from the University of Nottingham. |
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