Drug Delivery Technology Platform

Critical Pharmaceuticals drug delivery technologies enable the delivery of biological and challenging small molecule drugs by long acting depot injection or nasal spray.

CriticalMix injectable depot system uses supercritical carbon dioxide to encapsulate drugs in regulatory approved polymers for sustained release applications. Studies on more than thirty proteins and peptides have shown that CriticalMix maintains protein structure and activity and can sustain release over periods of weeks to months.

CriticalSorb is a novel absorption promoter able to efficiently deliver biologic drugs nasally. Clinical and preclinical studies have not only shown that it is highly effective in increasing the absorption of challenging molecules including proteins and peptides across the nasal mucosa, but that it is also well tolerated. CriticalSorb has the potential to provide a viable alternative to injection for a wide variety of drugs.

Critical Pharmaceuticals actively partners its drug delivery technologies and candidate drugs with pharmaceutical and biotechnology companies.